Senior Electrophysiologist

As a solutions-based company, Precise Systems is focused on innovation in support of the warfighters and aligning our expertise to deliver the highest quality of service. Powered by our highly skilled workforces, we provide expert consultation on network and weapons systems acquisition programs, maintenance/modernization programs, and sustainment programs with solutions in Digital Transformation, Advanced Engineering, Physical Sciences Research, Platform Lifecycle Support, and Technical Services. Since our establishment, we have demonstrated and perfected our ability to manage the customer's needs, no matter how complex – offering exceptional service and the Precise solution.

We are currently seeking a Senior Electrophysiologist with advanced experience in electrophysiology, molecular biology, and tissue culture. The candidate should have a well-demonstrated experience record in electrophysiology, particularly in patch clamping of voltage-gated and/or ligand-gated ion channels, and molecular and cellular signaling associated with ion channels. The candidate will be supporting efforts with a heavy emphasis on electrophysiology and cutting-edge instrumentation. Therefore, applicants who are willing to establish their own workflows and provide meaningful creative and technical leadership are highly desired.

All work is performed on-site, in Edgewood, MD, 5 days per week. Remote work is not authorized. 

Duties: 

• Conduct electrophysiology assessments on overexpression cell lines
• Measure calcium handling on multiple platforms on induced pluripotent stem cells or overexpression cell lines
• Perform screening of compounds of interest and their effect on ion channel activity, whether that be in cell lines, induced pluripotent stem cells, or primary cells. This includes neuronal cells cardiomyocytes, organoids, etc
• Keep detailed records of laboratory operations and compile data in regular technical reports.

Required Education:

• Must have a Master’s degree with five years of experience or a Ph.D. with a background in Electrophysiology, Biochemistry, and Molecular biology techniques.

Required Experience:

• Hands-on experience with the patch clamp technique (automated, manual or both)
• Understanding of ion channel physiology, cell signaling associated with channel function and dysfunction
• Hands-on experience with at least one of the following: 2D cell culture (overexpression cell systems such as HEK, CHO, etc.), primary cells, and induced pluripotent stem cells
• Must have some hands-on experience with drug screening or toxicological assessments, with willingness to work with toxic compounds of interest
• Must be able to design, plan, and execute experiments to understand electrophysiological effects of compounds of interest
• Demonstrated technical/scientific leadership skills and a passion for problem-solving
• Excellent oral and written communication skills
• Able to work productively in an interdisciplinary team environment.

Desired Experience:

• Fundamental skills in tissue culture and molecular biology techniques

Must be able to obtain and maintain a Secret security clearance. Due to the sensitivity of customer-related requirements, U.S. Citizenship is required. 

Precise Systems and its subsidiaries are committed to an inclusive and diverse workplace that values and supports the contributions of each individual. This commitment and shared Vision and Values of Integrity, Respect, and Responsibility allow us to leverage differences, encourage innovation, and expand our success in the global marketplace. Precise Systems and its subsidiaries are Equal Opportunity /Affirmative Action Employers. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, protected veteran status, status as an individual with a disability, or any legally protected status under federal, state, or local law.