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New York Genome Center


Senior Software Engineer I

IT + Computing

New York, NY
ID: 709-105

Welcome to the New York Genome Center (NYGC), where our Software Engineering Team is at the forefront of genomics technology, driving groundbreaking discoveries with global impact. We empower diverse genomics research projects, turning raw sequencing data into actionable clinical insights. Advancing genomics technology sparks revolutionary discoveries. Our team pioneers sequencing tech, amassing expertise in acquiring, analyzing, and applying genomic data on an unmatched scale. We innovate tools that expedite NYGC's research missions and scientific progress. At NYGC, our Software Engineering Team is dedicated to advancing genomics, turning data into knowledge, and shaping healthcare and beyond. We're genomics technology pioneers, facilitating discoveries that shape the world. Join us on this transformative journey into the future of genomics.

The New York Genome Center is seeking an accomplished Senior Software Engineer with a solid foundation in full-stack development and expertise in cloud migrations, cloud-native services, and integrating external solutions. In this role, you will be pivotal in advancing our application platform, making individual contributions, and collaborating with a team. You will craft high-caliber software that upholds industry standards, embodies efficient coding practices, follows DRY (“don’t repeat yourself”) programming principles, and aligns with our organization's dynamic requirements.

Key Responsibilities:

Including but not limited to the following:

  • System Architecture: Develop modular, scalable systems with RESTful web APIs.

  • Full-Stack Engineering: Deliver automation-first solutions across the full technology stack.

  • Coding Excellence: Employ modern coding practices focusing on Python 3 for maintainable, scalable code.

  • Quality Assurance: Create robust regression tests to ensure software integrity.

  • Cloud Leadership: Guide the transition of homegrown applications to cloud environments like GCP and AWS.

  • Product Oversight: Engage in product backlog management, requirements gathering, and solution validation.

  • Peer Review: Perform thorough code reviews, enhancing code quality and knowledge sharing.

  • Expert Advice: Offer technical guidance on architecture and best practices.

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties, or responsibilities required of the employee for this job. Responsibilities may change at any time, with or without notice.

Required Skills:

  • Education: Bachelor's in Computer Science/Engineering or related field.

  • Experience: 6+ years (or Master's plus four years) in relevant roles.

  • Quick Learner: Ability to quickly grasp new domains and apply technical knowledge.

  • Leadership: Demonstrated autonomy in leading small to mid-sized projects.

  • Tech Proficiency: Strong object-oriented programming skills in Python 3, React, or similar technologies.

  • Cloud Savvy: Hands-on experience with GCP, AWS, and RESTful APIs.

  • Middleware Insight: Capability to develop middleware for diverse system integration.

  • SDLC Knowledge: Well-versed in SDLC practices, including version control, testing, code review, and maintenance.

  • Database Acumen: Working knowledge of PostgreSQL and data warehousing with BigQuery.

  • Communication: Exceptional listening and communication abilities.

  • Mentorship: Experience in guiding software engineers.

Preferred Skills:

  • Database Mastery: In-depth knowledge of PostgreSQL and BigQuery.

  • Infrastructure Expertise: Proficiency with Docker and Terraform.

  • CI/CD Experience: Skilled in continuous integration and delivery practices.

  • Regulatory Understanding: Background in developing software compliant with FDA or HIPAA regulations.

  • Security Consciousness: Awareness of application security and identity management.

We welcome passionate Senior Software Engineers eager to contribute to groundbreaking genomic research and technological innovation. If you want to make a substantial impact with your full-stack expertise, NYGC invites you to apply.

Don’t meet every single requirement? Studies have shown that women and people of color are less likely to apply for jobs unless they meet every single qualification. At NYGC, we are dedicated to building a diverse, inclusive, and authentic workplace, so if you’re excited about this role but your experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply anyway. You may be just the right candidate for this or other roles.

About NYGC: A cutting-edge environment for genomics

NYGC is an independent, nonprofit academic research organization advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the-art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar), neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer.

Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community.

Work Flexibility

NYGC has established a flexible work policy to allow employees and other staff to balance their work, personal commitments, and commuting challenges. The incumbent in this position is eligible for a flexible work schedule and/or a hybrid work schedule, with supervisory approval.

Salary & Benefits

The pay range for this position is $116,000-153,000 per year; we expect to pay around $137,000, but the base pay offered may vary depending on job-related knowledge, skills, and experience. 

In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. This includes Medical/Dental/Vision for employees & dependent(s); Vacation, Holidays, Sick, and Other Leave, including a paid winter break; a 401(k) match; Life Insurance; Flexible Spending Accounts; employee Tuition Reimbursement; flexible schedules and telework options for some positions; an Employee Assistance Program; and much more.

Equal Opportunity

Diversity, equity, and inclusion are central to NYGC’s core mission. We strive to create a workplace environment that is welcoming and fair to all, regardless of race, ethnicity, gender, sexual orientation, physical ability, or religion. We believe that when people of various backgrounds, life experiences, and perspectives work together in an inclusive and equitable environment, we gain new and valuable perspectives that otherwise would have been missed. Valuing and supporting all NYGC employees as individuals while helping them realize their full potential is critical to promoting greater collaboration, innovation, and discovery – fostering a sense of belonging for our greatest strength, our people. We recognize that there is still work that will require sustained commitment from the entire organization.

The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

FLSA Status – Exempt

This position is eligible for visa sponsorship and relocation assistance.


This position is located at 101 Avenue of the Americas, 7th Floor, New York, NY. View the Google Map in full screen.