We are looking for a highly motivated, independent but team-oriented Associate Scientist II with experience in next-generation sequencing to work in our high throughput production lab’s library prep team.  Main responsibilities include DNA and RNA library preparation and process optimization. This position reports to the Library Prep Supervisor.

Key Responsibilities

• Carry out procedures associated with DNA & RNA sequencing on sequencing platforms, including DNA/RNA library preparation, sample extraction, quantification & preparation, and sequencer operation;
• Analyze current process procedures and provide feedback for their optimization and improvement, documenting processes, proposing method improvements, and troubleshooting assays, as needed;
• Perform various DNA & RNA library preparations using manual and automated protocols via liquid handlers (Hamilton STAR, Sciclone);
• Perform quality control of the samples and raw sequencing data;
• Conduct other laboratory work, as needed;
• Author/edit standard operating procedures;
• Track all work and issues in the appropriate databases and Laboratory Information Management Systems (LIMS);
• Become proficient using NYGC’s LIMS tracking system to accurately perform day-to-day tasks.

Requirements & Qualifications 

• Bachelors’ degree in Molecular Biology, Biotechnology, Biochemistry or related field, plus laboratory experience in nucleic acid research required;
• 2 years of NGS experience or 3+ years of equivalent relevant experience.
• Experience with automated liquid handlers preferred;
• Solid knowledge of molecular biology equipment and related protocols (including RNA and DNA preparation, RNA and DNA quantification, hybridization, PCR, multiplex amplification and bead-based solutions) highly preferred;
• Demonstrates intermediate Excel skills (chart, formula manipulations), familiarity with Microsoft Word, PowerPoint, preferably with Mac OS;
• Good general laboratory and organizational skills, including the ability to work independently and efficiently are essential;
• Ability to multitask is a must, along with an orientation toward teamwork and cooperation;
• Strong creative thinking and problem-solving skills; and,
• Excellent communication skills required.

Competencies

• Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments.
• Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so.
• Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity.

Work Flexibility

NYGC has established a flexible work policy to give employees and other staff more ability to balance their work, personal commitments, and commuting challenges. The incumbent in this position is expected to work onsite 5 days per week and is eligible for a flexible work schedule, with supervisory approval.

Salary & Benefits

The pay range for this position is $61,000-$71,000 per year; the base pay offered may vary depending on job-related knowledge, skills, and experience.

In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. This includes Medical/Dental/Vision for employees & dependent(s); Vacation, Holidays, Sick, and Other Leave, including a paid winter break; a 401(k) match; Life Insurance; Flexible Spending Accounts; employee Tuition Reimbursement; flexible schedules and telework options for some positions; an Employee Assistance Program; and much more.

About the New York Genome Center

The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer.

Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with twelve leading academic medical centers and research universities in the New York region and beyond, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. 

Equal Opportunity

Diversity, equity, and inclusion are central to the core mission at the NYGC. We strive to create a workplace environment that is welcoming and fair to all regardless of race, ethnicity, gender, sexual orientation, physical ability, or religion. We believe that when people of various backgrounds, life experiences, and perspectives work together in an inclusive and equitable environment we gain new and valuable perspectives that otherwise would have been missed. Valuing and supporting all NYGC employees as individuals while helping them realize their full potential is critical to promoting greater collaboration, innovation, and discovery – fostering a sense of belonging for our greatest strength, our people. We recognize that there is still work to be done that will require sustained commitment from the entire organization. 

The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

FLSA Status – Exempt 

This position is not eligible for visa sponsorship or relocation assistance.