Skip Navigation

New York Genome Center


Bioinformatics Analyst, Computational Biology

Computational Biology

New York, NY
ID: 677-105

This position at the New York Genome Center is within the computational biology group and will report to a Bioinformatics Scientist. As a Bioinformatics Analyst, you will contribute to the analyses of transcriptome sequencing data (both bulk and single-cell RNA-Seq) generated at NYGC. This includes the maintenance, benchmarking, and continuous improvement of our processing pipelines, as well as participation in downstream analyses. Additionally, you will apply and implement various tools and algorithms to analyze transcriptome data, collaborate with NYGC staff on developing new tools and with external investigators on the integration of functional genomics results within their scientific projects.


Key Responsibilities:

  • Contribute to setup, management and maintenance of genomic data processing pipelines;
  • Analyze sequencing data using the established pipeline(s);
  • Perform appropriate QC measures;
  • Stay current on innovations in RNA sequencing technologies and analyses;
  • Benchmark new tools for RNA-seq and single-cell RNA-seq data analysis and propose improvements;
  • Support and contribute to the development and implementation of innovative computational approaches for the analysis of large sequence datasets from NGS technologies;
  • Participate in collaboration with external and internal researchers on the analyses of NGS data;
  • Interpret and present the results of the computational and statistical analyses to collaborators and co-workers;
  • Work with the software engineering team to ensure pipeline upgrades and new pipelines are properly implemented in our production workflow manager;
  • Assist collaborators with data access, analysis, and interpretation;
  • Interact daily with other bioinformatics analysts/programmers;
  • Publish results in scientific journals and give presentations at conferences;
  • Participate in community outreach.


Position Requirements

  • Bachelor’s degree in bioinformatics, computational biology, genetics, computer science or similar with at least 2 year’s work/research experience, or a Master’s degree;
  • Experience in python and R required, as well as willingness to learn new programming languages as necessary to collaborate at NYGC;
  • 1+ years’ experience working with next generation sequencing data preferred (ideally human genomics), including experience using standard RNASeq analysis software (including samtools, GATK, Picard, bedtools, etc);
  • Excellent written and verbal communication skills required.


The requirements listed are representative of the knowledge, skill, and/or ability required for this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of the role.


Don’t meet every single requirement? Studies have shown that women and minorities are less likely to apply to jobs unless they meet every single qualification. At NYGC we are dedicated to building a diverse, inclusive and authentic workplace, so if you’re excited about this role but your past experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply anyway. You may be just the right candidate for this or other roles.



  • Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments.

  • Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so.
  • Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity.


Work Flexibility

NYGC has established a flexible work policy to give employees and other staff more ability to balance their work, personal commitments, and commuting challenges. The incumbent in this position is eligible for a flexible work schedule. We prefer a candidate who can work onsite fulltime, but we are open to a hybrid remote work arrangement for this position, with supervisory approval.



The pay range for this position is $82-105k per year; base pay offered may vary depending on job-related knowledge, skills, and experience. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. 


About the New York Genome Center

The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer.


Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with twelve leading academic medical centers and research universities in the New York region and beyond, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community.


Equal Opportunity

Diversity, equity, and inclusion are central to the core mission at the NYGC. We strive to create a workplace environment that is welcoming and fair to all regardless of race, ethnicity, gender, sexual orientation, physical ability, or religion. We believe that when people of various backgrounds, life experiences, and perspectives work together in an inclusive and equitable environment we gain new and valuable perspectives that otherwise would have been missed. Valuing and supporting all NYG employees as individuals while helping them realize their full potential is critical to promoting greater collaboration, innovation, and discovery – fostering a sense of belonging for our greatest strength, our people. We recognize that there is still work to be done that will require sustained commitment from the entire organization.


The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.


FLSA Status – Exempt

This position is eligible for visa sponsorship and relocation assistance.

This position is located at 101 Avenue of the Americas, 7th Floor, New York, NY. View the Google Map in full screen.