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New York Genome Center


Postdoctoral Research Associate, Lappalainen Lab


New York, NY
ID: 676-105

About the Lab

The Lappalainen lab studies functional genetic variation in the human populations by analyzing how genetic variants affect molecular and cellular traits, and how these cellular changes contribute to genetic risk for both common and rare diseases and traits. We analyze these questions both by computational genetics analysis of large multi-omic data sets from cells and tissues, and by experimental approaches based on CRISPR perturbations and single-cell sequencing. Our lab includes experts across the field of systems genetics, from statistical genetics and genomics to molecular genomics, and we work closely with our team in Stockholm, Sweden, as well as other collaborators locally and internationally.


About the Position

We are looking for a postdoctoral scientist eager to understand the impact of human genetic variation on gene expression and phenotypes at the cellular, tissue and physiological levels. The specific project would be tailored according to the interests and expertise of the postdoc, but possible projects include developmental GTEx, regulatory variant mapping and characterization large single-cell data from T cells, analysis of transcription factors as drivers of genetic associations and regulatory networks, and integration of population genetics and CRISPR perturbation data. In addition, we envision that the postdoctoral scientist will play a major role in developing new projects in a supportive team science environment. While this position is primarily for computational work, close collaboration with experimental scientists is encouraged. There are possibilities for co-mentorship with collaborating PIs at NY Genome Center and beyond.


To be considered for this role, please provide: 1) CV with a list of publications; 2) a short summary of your present and future research interests; 3) a list of three references and their contact information with your application.


Requirements & Qualifications

The ideal candidate will hold a PhD or MD-PhD and have prior research experience in functional genomics, statistical genetics, and/or computational biology and will have prior peer-reviewed publications. The candidate will be expected to plan and carry out research tasks independently and present findings on a regular basis.



  • Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments.
  • Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so.
  • Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity.


Salary & Benefits

The pay for this position is $88,000; this includes $70,000 base pay and an $18,000 per year taxable housing allowance.

In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. This includes Medical/Dental/Vision for employees & dependent(s); Vacation, Holidays, Sick, and Other Leave, including a paid winter break; a 401(k) match; Life Insurance; Flexible Spending Accounts; employee Tuition Reimbursement; flexible schedules and telework options for some positions; an Employee Assistance Program; and much more.


About the New York Genome Center

The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer.


Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community.


Please note: We care greatly about our employees’ wellbeing, so NYGC has moved to a fully COVID-19 vaccinated work environment. You must be vaccinated against COVID-19 to work at NYGC, even if you are working partially remotely. If you are selected to interview for this role, we will explain our vaccination policy (including medical and religious exemptions) and ensure you are comfortable moving forward with further interviews.


Equal Opportunity 

Diversity, equity, and inclusion are central to NYGC’s core mission. We strive to create a workplace environment that is welcoming and fair to all regardless of race, ethnicity, gender, sexual orientation, physical ability, or religion. We believe that when people of various backgrounds, life experiences, and perspectives work together in an inclusive and equitable environment we gain new and valuable perspectives that otherwise would have been missed. Valuing and supporting all NYGC employees as individuals while helping them realize their full potential is critical to promoting greater collaboration, innovation, and discovery – fostering a sense of belonging for our greatest strength, our people. We recognize that there is still work to be done that will require sustained commitment from the entire organization.


The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities. 


FLSA Status – Exempt

This position is eligible for visa sponsorship and relocation assistance.

This position is located at 101 Avenue of the Americas, 7th Floor, New York, NY. View the Google Map in full screen.